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BioSystems - paper somewhat related to (M,R)-systems



In the June 2005 issue of BioSystems, there is a paper entitled "A hybrid systems framework for cellular processes", by Cho, Johansson and Wolkenhauer. (see end of email) The paper invokes Rosen's (M,R)-system in its discussions. However, the paper is primarily about using "hybrid automata" for modeling of cellular dynamics.
 
I have only had a chance to skim the preprint of the paper, but it seems to me that the references to the (M,R)-system fail to appreciate its meaning and its implications. The paper seems to utilize Casti's interpretation of the (M,R)-system rather than Rosen's original intentions. The formalisms are those used by Casti, not those used by Rosen.
 
I may comment more when I've had more time to read it in depth. But I wanted to toss it out here to hear what others on the list think.
 
Regards,
Tim
 
P.S - There looks to be a couple of other interesting papers in that issue, particularly the one on "live memory".
 
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BioSystems, vol 80, issue 3 (273-282):
    doi:10.1016/j.biosystems.2004.12.002 
 
Preprint on Wolkenhauer's website:
http://www.sbi.uni-rostock.de/docs/p_mr_paper.pdf