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Re: Models and ecosystem balance/change...



At a lunch table in Santa Fe, Robert Rosen told several of us that he had discovered a different way (than energy minimization) to fold proteins. He said that he couldn't get any funding to develop it since the funding reviewers were, as I recall his statement, drawn from those with vested interests in the energy methods. I offered and he expressed interest in my finding a funding channel through the SBIR process. He never followed up on my request for comments on the proposal I began to draft.

Jack

Howard Pattee wrote:

At 11:38 PM 12/10/04 -0500, Judith wrote:

He [Rosen] used the example of protein folding to show that genes only code for the protein sequence, but in order for the protein to become active, it has to fold into a "tertiary" shape, which proteins in living systems spontaneously do. But how? That's the kind of thing that needs looking into.


HP: Since Rosen's last pessimistic views of protein folding (e.g., LI p. 270) a new discipline has been looking into it. See for example http://folding.stanford.edu/science.html
or Google "protein folding".


Howard