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Re: Models and ecosystem balance/change...
- From: Jack Park <***>
- Date: Sat, 11 Dec 2004 06:13:23 -0800
At a lunch table in Santa Fe, Robert Rosen told several of us that he
had discovered a different way (than energy minimization) to fold
proteins. He said that he couldn't get any funding to develop it since
the funding reviewers were, as I recall his statement, drawn from those
with vested interests in the energy methods. I offered and he expressed
interest in my finding a funding channel through the SBIR process. He
never followed up on my request for comments on the proposal I began to
draft.
Jack
Howard Pattee wrote:
At 11:38 PM 12/10/04 -0500, Judith wrote:
He [Rosen] used the example of protein folding to show that genes only
code for the protein sequence, but in order for the protein to become
active, it has to fold into a "tertiary" shape, which proteins in
living systems spontaneously do. But how? That's the kind of thing
that needs looking into.
HP: Since Rosen's last pessimistic views of protein folding (e.g., LI p.
270) a new discipline has been looking into it. See for example
http://folding.stanford.edu/science.html
or Google "protein folding".
Howard