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Re: Colimits and Limits: Simplest SELF-REPRODUCING ORGANISM with a CATEGORICAL STRUCTURE

Tim,

Please see my picture/diagram  of the Simplest Complex Biological System model in my second posted manuscript in word. Hope you will find it as exciting as promised by Robert and I , longtime ago (35 years ago to be precise!).

Not to worry about the Word format; I managed to post it successfully after one failed attempt concerned with "being over the "500k" limit, for this group only-mm?",  but only in Word format. Having a pdf posted as well would be very useful. Moreover you have my 'new/old' lecture on "Natural Transformations in Molecular Biology." that was  just updated and is also nicely posted, at least when I see it on my  Windows Millennium  Word  version for the laptop, with lots of biological examples , including a brand new SELF-REPRODUCING ORGANISM with a CATEGORICAL STRUCTURE , labeled as a "Primordial Organism" as an (M,R)-System with Replication-ReverseTranscription-SelfDuplication." that also shows the corresponding "rough  molecular structures associated with such FUNCTIONS"-- as these are known today. Please note that  two such important components shown in this 'new' Figure are the TELOMERE and the REVERSE TRANSCRIPTASE (or TELOMERASE); still not shown is the gene, hTERT, that codes for TELOMERASE. Both the Telomere and the Telomerase were correctly predicted based on my generalized categorical construction of the
simplest (M,R)-System or PRIMORDIAL ORGANISM in 1969 in my MS Thesis related to cancer modeling with generalized/ categorical (M,R)-systems, and published in several stages in 1970, 1971, 1973, 1977, 1983 and 1987.  These two predictions I made in 1969 were confirmed experimentally thirty years later.  The experimentalists who discovered the reverse transcription process (well, just three of them, of course received the Sweedish prize that Robert thought "it's just  based on political games".    The Telomerase structure is very UNUSUAL, you might say even extraordinary, as it functions in reverse to what a 'DNA' gene normally does, it transfer code from RNA-bound-in-the-Telomerase Protein/Enzyme itself, just as predicted by our generalized, functorial construction of the simplest self-reproducing (M,R)-system  ("primordial organism") published 31 years ago (Baianu and Marinescu, 1973), that I reviewed and updated in 1987 (Baianu, 1987). If you are looking at my figure in the second posted paper, based on my 1983 and 1987 papers, you will see there the functorial-categorical, as well as structural 'picture' or diagram of the simplest "Complex Biological System". (It may sound like a contradiction of terms "simplest complex", but it is not,
that's the way it is.
Today I have my copy of Robert's exciting book "Essays on Life Itself." The softcover though will only be available in February 2005!!! Kind of slow in making money on books, aren't they?
Please also note that, unlike other people, I gave credit to all authors of relevant papers and books published on the subjects discussed, unlike others who did not, and aren't doing so even now. According to Nicolas Rashevsky himself : "they'd be the losers in the long run!" ; (and this one I heard at first hand, with Nicolas at my right and Robert at my left, back in 1970, in Toledo, Ohio)..

If the group were interested to see my review of this wonderful book by Robert Rosen, I'd be prepared to provide such a thorough review, but I'd like to keep the "copyright of my review".    Would that be acceptable to you?  Hope you'd post this email for me.  Such a review would clarify many of the issues in the postings that are still floating up
in the air, and to which open questions Robert does provide some very interesting, exciting answers in his book.

Hope you enjoy a great weekend, and when you have time, and if you are interested, wish you a happy reading of my two new posted articles!

Regards,

Ionel C. Baianu



At 09:33 PM 5/21/2004 -0400, you wrote:
Ionel,

Ugh....I am still having some trouble with the document, both in Word and
PDF format. It is definitely better than before, but still garbled in spots.
The HTML version is not cooperating with me either. There seems to be some
kind of forgetful functor action occurring between the original document and
the converted documents. :(

As I mentioned in my other message, I will be away some of this weekend, but
I will try to see what I can do when I get back.

Regards,
Tim

> -----Original Message-----
> From: icb [mailto:***]
> Sent: Friday, May 21, 2004 4:43 PM
> To: Tim Gwinn
> Subject: RE: Colimits and LIMITS in Categories and Supercategories of
> Biological Systems and Their Models
>
>
>
> Dear Tim:
>
> I am sending you again the correct form of the article still in word
> because I still don't have  at home Adobe 'writer', only reader 6 and it
> refuses to convert
> from word to pdf. I'd need the Adobe 'professional' for that, whereas at
> the office I barely managed to get myself logged in and started posting
> yesterday from the office. Please save the copies of the attached
> html and
> doc files and convert one of them to pdf. I still do not know how I can
> post files on your listserver from either location. Perhaps, you'd be so
> kind to look at the pdf before posting it for me looking for obvious
> problems with "arrows that moved by themselves". My student who
> helped with
> the updated and scanning of my BMB SYMPOSIUM, 1971 paper is still at the
> beginning and does not see yet the advantages of text-only-editing that
> prevents arrows and diagrams for taking on a life of their own,
> if you will
> excuse this attempt at a categorical pun, intended.
>
> Let's hope we got it right the second time round!
>
> Best regards and happy readings,
>
> Ionel
>
>
> At 09:28 AM 5/21/2004 -0400, you wrote:
> >Ionel,
> >
> >Aren't computers wonderful? At least the text came through reasonably
> >unscathed. :)
> >
> >Once you have a corrected version, you should be able to add
> that file as an
> >attachment to your email and post it that to the list. Or, you
> can send it
> >to me and I can post it.
> >
> >I agree that the Toronto tutorial is very limited. I have yet to
> find what I
> >consider to be a "good" book on category theory, for someone
> with some set
> >theory knowledge, but not an advanced mathematician or computer
> scientist.
> >
> >Regards,
> >Tim
> >
> > > -----Original Message-----
> > > From: Ionel [mailto:***]
> > > Sent: Thursday, May 20, 2004 10:44 PM
> > > To: Tim Gwinn
> > > Cc: Professor I.C. Baianu
> > > Subject: Re: Colimits and LIMITS in Categories and Supercategories of
> > > Biological Systems and Their Models
> > >
> > >
> > > Tim, I am sorry about the problem with Diagram 4, in the
> posted document
> > > and the transmitted Word file; it's missing the Time
> Category, T, in its
> > > right corner, as becomes apparent from the description on the
> next page. I
> > > am planning to email you again a correct copy until I figure out
> > > if and how
> > > I can post a file, such as pdf or html at this site. The
> Toronto site is
> > > indeed very helpful, although the category theory offers much
> more than an
> > > introductory presentation can offer.
>