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Side Effects and internal models



Hello Folks,
 
It strikes me that the current news stories about "rampant type two diabetes having the potential cause of a lifetime's worth of a diet too high in carbs" fits in with my father's theories about internal models based on evolutionary contexts.
 
The mechanism at work in causing type two diabetes is very different from what causes type one. Type one is an autoimmune syndrome. Type two has confused people because it starts out so subtly and yet it ends up looking exactly like type one. Atkins believed it begins with "carb intolerance", whereby one's blood sugar spikes because of high intake of  carbs in the diet, the insuin has a corresponding spike which quickly clears the sugar out of the blood and stores it as fat, leaving the blood with a low blood sugar which causes a craving for more carbs. High blood sugar is toxic to the body, and damages many delicate tissues, which is why my father (a type one diabetic) had so many diabetic neuropathies. Among the tissues most damaged by sugar are the islet cells in the pancreas-- the very same cells that produce insulin.
 
So a cycle sets up of high blood sugar, high insulin, fat storage, low blood sugar, and cravings, which causes carb binging and more high blood sugar. And all the while, each spike is slowly damaging the body's ability to produce insulin (among other things). Added to that is the fact that as a person gains excess weight, insulin doesn't work as well and the body needs more of it to clear the blood. When it can't produce enough to clear the blood adequately, one has entered the realm of constant high sugar which damages tissue at a much faster pace. This is usually when people are diagnosed with type two diabetes. If this isn't controlled properly, the islet cells will be destroyed over time and a type two is now in the same boat as type one, needing insulin shots.
 
What Atkins was actually discussing is a phenomenon based on the fact that, for many of us, our physiological model calls for a different content of carbs, in relation to protein, in human diet. I think "carb intolerance" is a natural consequence when our intake differs substantially from the internal models we've got. So, the epidemic of diet-based diseases is the natural situation we would expect if the models differ from what the actual system is doing. We develop side effects.
 
However, this is an interesting juxtaposition of where the model is and where the system is: Both are physiological in this case, rather than science creating an artificial model and applying it to a natural system, and recommending action based on predictions from the model. That, in a nutshell, is what the USDA food pyramid is! It recommends carbs as the main source of intake for a healthy diet.
 
 I gave that set of ideas some thought and considered the notion that a huge proportion of human disease processes are caused by situations where we are not living or acting as our models prescribe. Since not everyone has the same models, it behooves us to figure out methods for discovering what our natural models are and then assess what we can safely alter and what has dangerous consequences if we mess with it. Seen in this light, things like "overuse injuries" are put in a new context. So is the body's reaction to chronic stress. Also, non-disease qualities of the body like talent that is body based, be it gross motor, fine motor, hand-eye, ear-eye, or some other coordination in a natural ability, may also be due to the influence of internal models based on some evolutionary context.
 
But this runs into the genetic influence, and I'm not sure whether the "internal model" is genetic... or if it is; whether it is entirely genetic. Perhaps it's an interaction between two or more different influences in some process that we haven't detected yet. Like time. The earlier discussion on the list about how women's menstrual cycles entrain when women live in close proximity to each other is proof for me that our bodies interact with all sorts of external phenomena that we don't perceive.
 
Interesting stuff....
 
Judith