Re: SciAm Dec. 2003 - DNA, Epigenetics, and Complexity

["James N Rose" <***>]

Thanks Tim for your detailed presentation of the
article "The Unseen Genome: Beyond DNA" by
W. Wayt Gibbs from the 12/2003 issue of Sci-Am.

And for the R. Rosen citations that answer the
inadequacy of the Gibbs argument.

It perpetually amazes me when biologists profer
arguments built wholly around hard-coding models:
one attribute, one genotype source for it.  All
WWGIbbs does is compound the problem by extrapolating
the same premise to the next level of organization.

Rosen, Eiseley, and others already made clear
the holistic interactive nature of 'nature' even at
the biochemical level, but the bulk of bio-scientist
just can't get with the program.  Sad.

Circa 1993 I came across Dean Falk's differential
studies of Australopithecines - gracile and robustus.

>From her descriptions of this crucial break in speciation,
ita was obvious to me that a significant speciation could
arise from an obscure single change in genome sequence --
specifically because (as Rosen demoted) the in situ environment
can be a powerful amplifier/transformer of any given
variations that occur.

I contacted Dean and received several papers from her,
then showcased her work on the Ceptual Institute
website, adding the interpretive performance model
I extended from the Integrity Paradigm.

In the A.gracile / A. Robustus case, as simple a thing
as a codon that changed the timing of competitive tissue
growth in the brain could have been sufficient to create
a whole new species.

I invite reasers to

<http://www.ceptualinstitute.com/genre/falk/homepageDF.htm>

and to

<http://www.ceptualinstitute.com/genre/falk/falkintegrity.htm>

in particular.



Looking for second order 'genomes' per WWGibbs is interesting,
but have a wholisticly grounded interactive paradigm is more important.

James Rose
12/14/03